Innovation Domain 03

Programmable Biology

We design biology with purpose — reengineering proteins, building gene circuits, and simulating engineered biologics in silico — lowering barriers to biological innovation for everyone.

Making biology designable.

Biology has always been a frontier of complexity. Today, we can read genomes, write genes, and design synthetic systems — but translating that capability into accessible tools and frameworks remains a challenge.

Our work in programmable biology bridges the gap between biological theory and experimental practice. We develop computational pipelines, simulation tools, and educational frameworks that empower researchers to conceptualize, validate, and build engineered biological systems.

Our research →
🧬
Genome Design
Predictive modeling and optimization of genomic sequences for desired functions.
Gene Circuits
Designing and simulating synthetic gene regulatory networks and metabolic pathways.
🔬
Synthetic Engineering
Building and validating novel biological constructs through computation and experiment.
📊
Systems Modeling
Creating quantitative models of biological processes to guide experimental design.

What we're building

Our active research directions tackle critical challenges in translating molecular features into living, functional biological systems.

Genome Predictive Modelling
Developing algorithms to predict phenotypic outcomes from genomic sequences — enabling rational design of biological systems.
Synthetic Gene Construction
Designing and optimizing synthetic genes and gene constructs for improved expression and function.
Phylogenomics & Evolution
Using computational approaches to understand evolutionary relationships and design evolutionarily stable biological systems.
Biomarker Discovery
Identifying and validating molecular features that predict disease, function, or response — enabling precision biology.

Experience programmable biology in practice

Our platforms and training programs bring programmable biology from theory into hands-on, practical application.

Explore the other domains

Discover our work in data & information science and machine learning — the three pillars of ChordexBio innovation.

Data & Information → Machine Learning